The Connection Between Erectile Dysfunction And Hyperuricemia


The relationship between the high level of uric acid and the inability to lasts an erection is inconceivable. The fact is that there is only statistical research to connect the two. There are still no scientific studies that can support the relationship between the two diseases.

But, when we apply logic and the basics of the human physiology, there is a relationship between the two diseases. You might wonder, “Which comes first? Hyperuricemia or Erectile dysfunction?”

This article aims to explain the relationship between the hyperuricemia and erectile dysfunction. When you read this, we can discuss the pathways or cycles of both the hyperuricemia and erectile dysfunction.

Which comes first between Hyperuricemia and Erectile Dysfunction?

Hyperuricemia is a condition wherein the body has a high level of uric acid. And it does not directly cause erectile dysfunction. However, hyperuricemia can cause gout that connects with erectile dysfunction. Does it make sense to you? No. gout does not cause erectile dysfunction, too.

The answer is at the cellular level. Do you know how the penis erects?

Erection relies on the chain of physiological and psychological reactions. The penis erects because of the increase in the flow of blood in the penile arteries and corpus cavernosum. Corpus cavernosum is a cavernous tissue in the penis. In addition, the increase in the blood flow occurs when the arteries and the muscle layer relaxes. The relaxation is caused by the cyclic guanosine monophostate. The synthesis of cyclic guanosine monophostate relies on the release of nitrogen oxide from the cells of the endothelial.

You may be confusing yourself with the biochemistry jargons. You just need to understand that the nitrogen oxide from the endothelial cells is important in the process of erection.

This article will not discuss the process of erectile dysfunction. However, the main cause of erectile dysfunction is when the flow of blood lacks. Especially in the penile arteries and corpus cavernosum. In addition, it can be the effect of the high levels of uric acid in the body. Uric acid can reduce the release of nitrogen oxide and can cause endothelial dysfunction. With the lack of nitrogen oxide, there will be no blood flow increase in the penile arteries and corpus cavernosum. It is when erectile dysfunction happens.

We can therefore say that hyperuricemia can cause erectile dysfunction in men.

Erectile Dysfunction before Hyperuricemia

Erectile dysfunction does not cause hyperuricemia. Still, there is a number of risk factors for erectile dysfunction and hyperuricemia. An example is that a patient with hypercholesterolemia may end up with both diseases. And there is a coincidence that hyperuricemia came first before erectile dysfunction.

Erectile dysfunction does not guarantee that you will also get Hyperuricemia when you suffer from erectile dysfunction. But, when you have hyperuricemia, there is a guarantee that you also suffer erectile dysfunction. You may not suffer from erectile dysfunction but there is a difficulty to get an erection.

Hyperuricemia, Gout and Erectile Dysfunction

Gout does not cause hyperuricemia. But, there are blogs and forums that say gout can cause Erectile dysfunction. They say that there is a higher risk of erectile dysfunction when they suffer from gout.

Gout does not cause erectile dysfunction, too. Nevertheless, there is a huge possibility of erectile dysfunction if you treat gout in a wrong way.

Gout patients take colchicine to relieve the symptoms of inflammation and pain temporarily. However, the sad thing to say is that colchicine has side effects. It can cause erectile dysfunction. It can also cause impotence in the process. Although colchicine relieves pain and inflammation, it also damages at the same time. Because colchicine inhibits the cell cycle, it also lowers the different types of cell in the body. It is because the cells will not be able to reproduce during the cell cycle. The damaged cells may include the red blood cells and the white blood cell neutrophil. White blood cell neutrophil is important for the immune system of the body. In addition, there is also a possibility that the reproductive cells can be damaged. Because of this, it can cause erectile dysfunction or impotency.


To remedy these diseases, it is important to reverse the hyperuricemia as soon as possible. Then you can avoid gout and erectile dysfunction.


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