We know that medications are very important for us people, most especially to those who are ill. Even though there is no guarantee for them to work, they are still guaranteed to have various side effects. In the actual fact, there are times that these side effects have a much better chance of settling in, instead of its relieving effect.
This truth is the same for the different medications for gout. Rather than lower the level of uric acid and avoid the pain and inflammation in the joint due to a gout attack, the exact opposite is what may happen.
This particular article wishes to explain the possible side effects of Zyloric. Both the short term and the long term consumption of this specific medicine may lead to a lot of conditions.
Zyloric…
Zyloric is a brand name of the allopurinol medication. Allopurinol falls under the Xanthine Oxidase Inhibitors medicine category. Furthermore, this certain medicine works thru slowing down the speed of chemical reactions in the body. This mainly helps in lowering or reducing the levels of uric acid in the blood, as well as in the urine.
Moreover, Zyloric is beneficial in the inhibition of the formation of the uric acid removal in various circumstances wherein the body produces uric acid in large amounts. These conditions may comprise gout and some other forms of kidney stones or certain types of kidney conditions. It might also be useful if you are currently in treatments for various conditions, including cancer.
Side Effects of Zyloric
This particular medication may create an illusion, which can make you become dependent on the drug. It can make you believe that it really is beneficial for the treatments of uric acid. In a strange manner, a certain individual who stopped taking Zyloric may have an above average level of uric acid. This doesn’t necessarily mean that Zyloric is a drug, which simply depends on the suggestion of its efficacy. Zyloric has its own mechanism that allows it to lower or reduce the uric acid level. However, there is more to it than just that.
Once a person already takes Zyloric, the uric acid level from the lab tests may seem to become lower. This is actually a fact. However, it is just for a short period of time. This is mainly because the Zyloric does not flush the uric acid nor stop its production. Furthermore, the only thing that Zyloric do is to delay the uric acid production. Therefore, the amount of the uric acid that is not made today will be created the next time, alongside the succeeding batch of the uric acid.
Zyloric actually does this by preventing the purine breakdown. Furthermore, since it is a Xanthine Oxidase Inhibitor, it disrupts the normal process of purine metabolism in the body. Purine is a macromolecule that is used by the body with the purpose of manufacturing the DNA’s nucleotides. Yes, it makes up the DNA. And therefore, it is present to anyone, anything, and to everywhere you go.
However, as what is aforementioned earlier, this purine is a macromolecule. Thus, it is not easy to excrete it out of the body. It must first be crashed into uric acid for us to get rid of it. Once the liver detects that there is purine in the bloodstream, it activates the Xanthine Oxidase which is primarily responsible for the breaking down of purine and turning it into uric acid.
On the other hand, this particular process can be interrupted by Zyloric. Zyloric is actually a purine analog, which has a construction that is almost alike with the structure of purine. Xanthine Oxidase will mistakenly recognize it as a form of purine. Thus making it too occupied by the medication. As soon as Zyloric is not already detected in the bloodstream, all the stacked or undisposed Zyloric will be transformed into uric acid. This may cause more austere gout attacks.
What’s good about Zyloric is that it will less likely damage the kidneys. Not unless if the uric acid goes through it and develops a uric acid kidney stone. Conversely, it may affect the liver. In fact, if you expose the liver to an excessive amount of Zyloric, it will get toasted.
Moreover, Zyloric may cause a Steven-Johnson Syndrome and Toxic Epidermal Necrolysis. These are both fatal skin conditions that may peel the skin even when you’re still alive. This is the worst side effects of Zyloric. The short term and long term consumption of Zyloric may cause either of the two illnesses.
Is Zyloric really worth taking? You decide on that!