Do you suffer from gout? Then you really know that the pain that it has is unimaginable and lingering. If you are not, then you are lucky. In spite of everything, who’ll ever wish or expect that the joints will one day get inflamed and will burn with pain. Well, I mean, the literal way. That having said, those who are suffering from gout really wishes to have a medication that may do them some miracle. One instance of which is a medication that is beneficial in reducing the levels of uric acid. One is allopurinol. Is it good to take allopurinol for gout? Read on to this article to know the answer!
Actually, allopurinol is a medicine that is really beneficial for gout. This article wishes to explain the use, the side effects, as well as the mechanisms of the allopurinol for gout.
Allopurinol for Gout
Allopurinol is actually a medication that is no stranger to those who suffer from hyperuricemia as well as gout. In fact, some does not want to live without allopurinol by their side. It is a treatment to their own pain. You, or maybe someone you love, might be one of them.
Allopurinol is actually a kind of medicine that falls under the xanthine oxidase inhibitor medicine category. This means that it may overpower the xanthine oxidase enzyme, which is essential for the purine break down. Furthermore, allopurinol bonds with the xanthine oxidase so that the purine stays in its original form, thus not producing uric acid. Basically, allopurinol cheats the system. Moreover, allopurinol is adept in using brute force to conquer xanthine oxidase enzyme. The liver will be exploited. Purine isn’t flushed out as the body doesn’t really treat it as a toxic since it’s important in the creation of the nucleotides.
Allopurinol for Gout: The Use
Hypothetically, allopurinol is an overwhelming pill, which may lower the uric acid level, in an instant! If you have been taking allopurinol, try to go to your doctor for a uric acid test after and then see various miracles that it does. Moreover, the uric acid may become lower. Additionally, allopurinol is beneficial in lowering the uric acid much faster. Genuinely, allopurinol is a very beneficial medication for this. Contrariwise, it’s effect is temporary only.
Allopurinol will never be adept of flushing the uric acid out of the body. It’ll not even have the capacity to stop the production of uric acid. Allopurinol just pauses it and intrudes it to be able for the body to catch up. Despondently, as the body tries to catch up, it may draw near in a wrong way.
The medication is usually prescribed anywhere in between 50 milligrams to 900 milligrams varying perceptibly on the sternness and common allopurinol gout medication, which is usually 300 milligrams per day. Furthermore, it is imperative that you have a regular test of uric acid while on this particular treatment. As well as to ensure that the prescribed dosage is proper for you. Take note that allopurinol is taken orally, every after a meal to reduce the possibility of an upset stomach. This is the reason why you should drink water when drinking this medicine.
Mechanisms of Allopurinol
Aforementioned earlier, the allopurinol is beneficial in pausing the production of uric acid. Well, even though there is no uric acid that will be produced for the interim, but there’ll be double later on.
As what we’ve said earlier, allopurinol is a xanthine oxidase inhibitor. As the effect of it sets in, the xanthine oxidase enzyme will not be capable of breaking down purine into uric acid. Instead, it tries breaking allopurinol down as the allopurinol acts like a purine. This just means that the uric acid will not be capable to upsurge for a moment.
Contrariwise, the body will not be able to stand so much purine. The worse thing here is that the purine will never be flushed out without being converted into uric acid. Therefore, all of that purine you’ve paused must be converted into uric acid in due course. Since there is too much purine that’ll be stocked, the body will rush the process of conversion. Therefore, the uric acid will come in a swarm assault. Henceforth causing a more severe gout flare-up.
Allopurinol for Gout: The Side Effects
If you’re allergic to allopurinol, you must not take it and if you take some other medications, it is significant to tell your doctor. This is since there could be a very serious drug interaction. Diarrhea, nausea, stomach upset, or drowsiness may take place.
Much rarer side effects that are more severe than those aforementioned, include the following:
- breathing problems
- loss of appetite
- eye pain
- vision changes
- signs of infection
- dark urine
To conclude, allopurinol has a good effect for the condition. However, you should consult your doctor first before using it.